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CAS Number: 215303-72-3
PubMed PMID: 26228681
inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP
Co-culture of hepatocellular carcinoma cells and human umbilical endothelial cells damaged by SU11274
Smiles: O=C(NCCS(=O)(=O)C1=CC=C(C=N1)C(F)(F)F)C1C=CC(Cl)=CC=1
SR9011 - REV-ERB Agonist. CAS# 1379686-29-9 Catalog No.:M66049-2S CAS Number: 215303-72-3SR9011, CAS No. 1379686 29 9, is a potent and specific synthetic REV ERB agonist that binds to REV ERB with an EC50 ~790 nM and REV ERB with EC50 ~560 nM. It also has good in vivo plasma brain exposure. The nuclear receptors REV ERB and REV ERB play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock
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